The 25 Best Sulfate Free Dandruff Shampoos

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If you’ve even a passing interest in shampoos you’d be aware that the use of sulfates in shampoos is a hugely controversial topic.

Some of the materials you’ll read are contradictory and some are misinformed. There’s a lot of misleading info. out there. The problem is that sulfates are found in most mainstream shampoos.

In this article, after speaking to four board-certified dermatologists and reviewing hundreds of dandruff shampoos, we’re going to tell you what we consider the best sulfate free dandruff shampoos on the market today.

But in addition to that, we’ll also explore the basic science of sulfates, explain what they do, how they do it, what the risks are and try to bust a few popular myths on the way. Giving you the tools you need to determine of sulfate free dandruff shampoos are for you.

What’s in this article:

The Winner – Best Non-Medicated Sulfate Free Dandruff Shampoo

Pharmaceutical Specialities™ Free & Clear Shampoo is our favorite sulfate free shampoo for dandruff sufferers.

While it isn’t a medicated shampoo, this shampoo is an innovative mix of cleansers and foaming agents that have been designed for sensitive skin sufferers. And they work very very well. We wish all shampoos were formulated with this degree of care and attention.

The shampoo washes well and has no discernible scent due to it being fragrance-free. It’s also free of preservatives, parabens and any ingredient we know of that can cause contact dermatitis.

If you have a sensitive scalp we simply can’t recommend this shampoo highly enough.

Pharmaceutical Specialities™ Free & Clear Shampoo
If you use a gentle non-medicated shampoo as part of your dandruff control regime make it this one. Outstanding.
buy now from amazon

The Winner – Best Medicated Sulfate Free Dandruff Shampoo

Sebclair Shampoo is our best sulfate free dandruff shampoo. It’s actually is our best-medicated dandruff shampoo period.

In our tests this Piroctone Olamine shampoo, designed to treat dandruff caused by Seborrheic Dermatitis, was simply the best and most gentle formulation on the market.

In addition to Piroctone Olamine, this shampoo contains Sorbitol – a humectant aka an active which attracts water to itself. When such an ingredient’s near your scalp, skin can be hydrated and soothed. Great news for dry scalp sufferers. It’s also an ingredient used to break down biofilms.

And instead of SLS, Seblair uses 5 extremely mild cleansing and foaming agents. The cleansing ingredients are all perfect for sensitive scalps, have no significant ingredients likely to cause contact dermatitis and this shampoo still washes oily hair and scalps extremely well.

Also of note, you’ll find a number of extracts that have antibacterial, antioxidant, anti-inflammatory and anti-microbial properties.

And on top of this, Sebclair uses an ultra-mild, natural preservative system, no essential oils, no fragrance, no parfum and no allergens.

Bottom line: If you have an extremely sensitive scalp but suffer from dry scalp or mild/moderate seb derm, Sebclair shampoo is the embodiment of your perfect remedy.

Sebclair Shampoo
An outstanding shampoo, formulated with precision and care, and the best dandruff shampoo we've seen this year.
buy now from amazon

The 25 Best Sulfate Free Dandruff Shampoos

After reading this and you have made the decision to avoid sulfates we have some good news for you – there are a number of sulfate/sls free shampoos about on the market now.

Here are some of our favorites.

Pharmaceutical Specialities Free & Clear Shampoo

Designed to treat Seborrheic Dermatitis, Dry Scalp and Psoriasis

Pharmaceutical Specialties formed in 1974 to “start a company to make better products than were commercially available for people with sensitive skin”. And boy, have they achieved it with this Free and Clear shampoo.

What is perhaps surprising on a website dedicated to dandruff treatments is that this isn’t a dandruff shampoo at all.

It’s rather a "a non-medicated, mild shampoo for sensitive skin and scalp.”

That said, we can’t use a medicated shampoo all the time, and this is my go to shampoo for those “between” washes.

BIOM8 Skin Conditioning Oil

Designed to treat Seborrheic Dermatitis, Dry Scalp

BIOM8 Skin Conditioning Oil is now part of my daily skin care routine. It’s as simple as that. I have lost count of the number of products I’ve reviewed over the years and I can count on one hand the number of products that have impacted me on this level.

If you suffer from dry skin, facial seb derm or rosacea I simply can’t recommend this product highly enough.

It even makes a good beard oil!

Maple Holistics Hydrate Shampoo

Designed to treat Dry Scalp

Maple Holistics Hydrate Shampoo has been superbly formulated to soothe and moisturize the scalp and hair. The ingredients have been carefully selected to decrease the chance that the product will irritate the skin. Using multiple low dose surfactants is a stroke of genius and only the fact the shampoo contains only one potential contact allergen says it all.

This is as close to perfection as you get in the commercial shampoo world.

I simply can't recommend this highly enough.

Nurture My Body Everyday Fragrance Free Shampoo

Designed to treat Dry Scalp

Nurture My Body Everyday Fragrance-Free Shampoo is an excellent gentle option for sufferers of a dry irritated scalp. The absence of any noteworthy irritants or allergens combined with the expert formulation of anti-inflammatory moisturizing ingredients makes an excellent change from the usual harsh surfactants and other toxins that lead to a vicious cycle of irritation and inflammation.

They've managed all of this in a shampoo that foams and washes well.

It's not particularly cheap, but this is simply one of the finest dry scalp shampoos out there.

Sebclair Shampoo

Designed to treat Seborrheic Dermatitis, Dry Scalp

Calling all sensitive scalp sufferers, if you haven’t yet found an anti-dandruff shampoo your scalp can tolerate, you haven’t yet found Sebclair shampoo. A piroctone olamine, Malassezia yeast quelling formula with extremely mild yet highly effective cleansers, accompanying scalp hydrators, flake fighters and natural anti-inflammatories. No fragrance, no essentials oils, no allergens. Sebclair shampoo really does stand out in our anti-dandruff crowd.

Bioderma ABCDerm Babysquam

Designed to treat Seborrheic Dermatitis and Cradle Cap

If your babe’s crusty cradle cap’s only getting worse, it’s time to try a leave on treatment – one which doesn’t leave your baby’s scalp looking like a grease ball. Enter Bioderma’s ABDderm Babysquam keratoregulating cream a 14 ingredient formula made from sensitive, hypoallergenic, moisturising, soothing and barrier building ingredients.

Useable 7 days a week with no fragrance or harsh preservatives Bioderma’s ABDderm Babysquam keratoregulating cream respects, repairs and conditions away crusty cradle cap.

Dead Sea Spa MAGIK Mineral Shampoo

Designed to treat Seborrheic Dermatitis, Dry Scalp and Psoriasis

Dead Sea Spa MAGIK Mineral Shampoo is a combination shampoo containing both salicylic acid and zinc pyrithione.  The thinking behind this shampoo is that the salicylic acid will soften and exfoliate existing build up and the zinc pyrithione will help prevent new build up from forming.

I’m generally a big fan of combination shampoos and this is no exception.  The shampoo feels great, has a nice light smell and leaves the hair feeling extremely soft.  It only contains one known contact allergen too - cocamidopropyl betaine.

If you suffer from mild seb derm I can’t recommend this highly enough.

Vichy Dercos Anti-Dandruff Sensitive Shampoo

Designed to treat Seborrheic Dermatitis

One of the best and mildest shampoos out there for seb derm sufferers with sensitive skin.

Containing both Piroctone Olamine and Salicylic Acid as well as being SLS free, paraben free, artificial color free this shampoo has an absolutely outstanding choice of active and inactive ingredients.

There are still two or three chemicals in there that some may find irritating. Otherwise this would have been a five out of five performer.

Neutrogena T/Sal Therapeutic Shampoo

Designed to treat Seborrheic Dermatitis and Psoriasis

Quite simply the best pure Salicylic Acid shampoo we’ve yet reviewed. The shampoo contains 3% Salicylic Acid combined with a fragrance free, sulfate free and virtually every other nasty ingredient free formulation. It does this and still feels luxurious when washing.

Neutrogena should be exceptionally proud of this top top class shampoo.

Tru Moroccan Repair Shampoo

Designed to treat Dry Scalp

An impressive dry scalp treatment shampoo with an innovative formulation.

I have to applaud any company that can formulate a shampoo with so few allergens. The fact that it washes so well is marvelous. For those not sensitive to Cocamidopropyl Betaine, Phenoxyethanol or fragrances - this is an excellent shampoo.

Eucerin Dermocapillaire Calming Urea Scalp Treatment

Designed to treat Dry Scalp

This dry scalp treatment isn’t a shampoo at all, but rather a leave on moisturizer that you apply to your hair after washing.

The advantage of this approach is that, while shampoos are designed to clean (and all the sensitizing issues that come with that) this treatment is designed to moisturize and nothing else.

You’re free to use the shampoo of your choice and us this treatment in combination.

It’s an excellent approach that I hope other manufacturers take notice of.

Scalp 18 Coal Tar Shampoo

Designed to treat Seborrheic Dermatitis and Psoriasis

Scalp 18 Coal Tar shampoo is a 2% coal tar formulation that has a number of added essential oils to further nourish and soothe the scalp.

These essential oils do contain fragrance but if you're not sensitive to fragrances then this is a superb shampoo.

It is extremely gentle and washes like a high end salon shampoo.

If you’re not sensitive to fragrances then I wouldn’t hesitate to recommend this shampoo.

Maple Holistics Tea Tree Oil Shampoo

Designed to treat Seborrheic Dermatitis, Dry Scalp

Maple Holistics Tea Tree Shampoo is an outstanding Tea Tree shampoo for treating Dry Scalp or Seb Derm. It doesn’t contain any artificial coloring or fragrance, sulfates, parabens, or carcinogens. It contains only three potential contact allergens, with two of the three being tea tree and rosemary essential oils.

The combination of cleansing agents used are gentle, effective and innovative while the shampoo smells ace and washes even better.

If you're looking for a tea tree shampoo, I can't recommend this highly enough.

Cleure Volumizing Shampoo

Designed to treat Dry Scalp

Cleure Volumizing uses only a handful of skin conditioning agents and gentle cleansers to treat a dry scalp.

It contains only two potential irritants that should be considered low to moderate concerns, compared to other much harsher alternatives. This shampoo doesn’t use any sulfates, parabens, artificial fragrances, dyes, alcohol, salicylates, formaldehyde, or SLS, making it a good option for those with sensitive scalps who typically react to less gentle, conventional shampoo and other personal care products.

Unless you have severely sensitive skin and are highly reactive to any potential irritants, we suggest trying this shampoo from Cleure and seeing if it calms your sensitive skin, and helps to clear up any dryness and itchiness on your scalp.

Puracy Natural Shampoo

Designed to treat Seborrheic Dermatitis, Dry Scalp and Psoriasis

Puracy Citrus Mint Natural Shampoo offers a great natural alternative to the many sulfate laden shampoos on the market today. Whether you are looking for an everyday use shampoo, or one that you can rotate your medicated dandruff shampoo with, we’d recommend trying the Natural Shampoo.

Because there are essential oils in the formula, we recommend caution to anyone who is sensitive to fragrances, or sensitive or allergic to any of the ingredients.

Otherwise, you’re looking at an expertly formulated shampoo that, for once, lives up to the manufacturer’s promises.

Sebclair Non-Steroidal Cream

Designed to treat Seborrheic Dermatitis, Dry Scalp

Sebclair Non-Steroidal Cream is an anti-fungal, piroctone olamine based treatment partnered with a trophy cabinet of natural anti-inflammatory actives. If you have a mild to moderate case of seb derm, hate steroids and love naturals Sebclair is for you. Best bit – there’s only two known allergens or irritants.

Free and Clear Medicated Anti-Dandruff Shampoo

Designed to treat Seborrheic Dermatitis

Do you have an extremely sensitive scalp in need of anti-dandruff help? Do you suffer from mild to moderate seb derm?  Meet your new best friend.  Free & Clear’s Medicated Anti-Dandruff Shampoo contains zero allergens, zero irritants, zero sensitizers formula based on 2% zinc pyrithione. An active ingredient able to improve the health of dandruff affected skin while also helping pacify dandruff causing overgrowths of the Malassezia yeast.

I simply can't recommend this shampoo highly enough.

Bella B, Bee Gone Cradle Cap, Baby Shampoo

Designed to treat Seborrheic Dermatitis and Cradle Cap

Are you looking for a natural solution to your baby’s crusty cradle cap? Want a formula that works with your skin to help restore a healthy scalp? Then look no further than Bella B’s Bee Gone Cradle Cap Baby Shampoo with oatmeal, tea tree oil, shea butter and more for helping restore what makes your baby's scalp healthy. Free of parabens, animal by-products, harsh cleansers and preservatives, the hypoallergenic formula makes Bella B’s bee gone cradle cap baby shampoo a great solution for the everyday care of your baby's scalp.

Mustela Cradle Cap Foam Shampoo For Newborns

Designed to treat Seborrheic Dermatitis and Cradle Cap

Anti-cradle cap shampoos designed to be used from the very first day of your babe’s life are hard to come by. And in the promise of finding one, you want to be 100% sure of its safety. Mustela foam shampoo for newborns is a diamond in the rough, featuring well proven anti-cradle cap/anti-dandruff actives with above and beyond safety testing in a daily use formula.

It is worth bearing in mind that it isn't fragrance-free, and salicylic acid can cause dryness after prolonged usage.  But as a treatment to combat established doses of cradle cap - you'll struggle to find a more effective treatment on the market.


Designed to treat Seborrheic Dermatitis and Psoriasis

Capasal have taken the unique step of combining 1% Coal Tar with 0.5% Salicylic Acid and added coconut oil.

It's perhaps the most original and interesting shampoo formulation we've yet seen

While the shampoo is SLS, fragrance and paraben free there are still a few known contact allergens in there. Unfortunately it smells like a coal tar shampoo too.

That aside Capasal is an excellent shampoo for those who suffer mild to moderate scalp psoriasis.

Denorex Extra Strength 2 in 1 Dandruff Shampoo and Conditioner

Designed to treat Seborrheic Dermatitis and Psoriasis

Denorex isn’t the gentlest shampoo, but with 3% Salicylic Acid it’s as strong as you’ll find OTC.

If you don’t use it too frequently and you suffer from mild to moderate psoriasis or seb derm, Denorex is very effective treatment.

Aubrey Organics Green Tree Clarifying Shampoo

Designed to treat Product Build Up

A gentle clarifying shampoo may sound like a contradiction in terms, but Aubrey Organics have done a fantastic job formulating a clarifying shampoo with mild ingredients.

It’s possibly the gentlest clarifying shampoo we’ve reviewed yet.

It smells nice, it will clarify your scalp, it will help remove dandruff caused by product build up.

But this comes at a cost – it will dry your scalp if used too much.

Like all clarifying shampoos – use absolutely only when needed.

Giovanni 50:50 Balanced Hydrating-Clarifying Shampoo

Designed to treat Product Build Up

The self proclaimed “natural-product industry leader”, Giovanni shampoos are multiple award winning shampoos entirely manufactured in the USA.

The 50:50 hydrating/clarifying shampoo has an ambitious purpose; to both moisturize and clarify.

It largely achieves this, although some of you may wish to use a conditioner too.


Pura Dor Argan Oil Scalp & Dandruff Treatment

Designed to treat Seborrheic Dermatitis, Dry Scalp

Pura's D'or Argan Oil shampoo features an interesting formula that combines traditional therapy and herbalism.

It wears a premium price tag, but it is truly a premium product.

The active ingredient in Pura's product is the familiar zinc pyrithione. It also includes aloe vera and grapefruit seed extract, which have antifungal and antioxidant properties, and a number of fragrant essential oils.

Normally, shampoos containing argan oil send up a red flag for people with seborrheic dermatitis. The oleic acid content can exacerbate the condition. However, the amount present determines the sensitivity level, and a little should have no impact.

After using the shampoo, we found that it delivered a great performance without producing adverse reactions.

If you're sensitive to fragrance, cocamidopropyl betaine or phenooxyethanol, you may want to steer clear of this shampoo, but for many dandruff sufferers, it can achieve complete control of symptoms while providing a pleasant and surprisingly sudsy washing experience along with reliable treatment results.

Maple Holistics Sage Shampoo for Heavy Dandruff

Designed to treat Seborrheic Dermatitis, Dry Scalp

Maple Holistics has created an innovative and gentle shampoo using essential oils rather than traditional active ingredients to control dandruff. Despite being marketed as a sage shampoo, it actually contains a number of essential oils including tea tree, jojoba, sage, tea tree, rosemary, peach kernel and spikenard oils. The thick, white, pearly shampoo smells like tea tree oil mixed with other herbal notes. Considering its lack of sulfates, its foaming abilities are impressive, and it provides an excellent washing experience. Due to the inclusion of panthenol, it leaves your hair feeling extremely soft. Although older formulations contained undesirable ingredients, the only contact allergen listed in the current formula is cocamidopropyl betaine.

If you suffer from mild seborrheic dermatitis or dry scalp, and you’re not sensitive to the fragrances in essential oils, this is a gentle, well-formulated shampoo that we highly recommend.


If you haven’t seen your favorite shampoo listed, chances are we have and it can be found if you check out all our sulfate free dandruff shampoo reviews.

How we chose the winners

All our reviewers are experts in product formulation, haircare, qualified pharmacists or haircare experts.

They assess the formulation of the shampoo, deconstructing the shampoos to their constituent parts and describe the key ones in detail. In addition, they highlight the presence of any one of over 100 ingredients that can potentially itch, irritate and exasperate your condition.

Unlike most review sites, our reviewers personally try every shampoo they review and they also assess how the shampoo washes, how it smells and costs. These may be medicated shampoos, but that doesn’t mean we want to compromise on a little bit of luxury!

We applied these same principles when choosing our best coal tar shampoo.  For example, the winner is one of the gentlest dandruff shampoos we’ve reviewed.  It’s not perfect, but compared with the others it washed slightly better and the fact that it was fragrance-free gave it another edge.  That’s not to say it’s the best coal tar shampoo for you.  For example, Scalp 18 shampoo contains slightly more coal tar but is fragrance heavy.  They’re both outstanding shampoos, so we eventually chose the gentlest formulation.

What are sulfates?

Sulfates are used in shampoo to help remove sebum and dirt from your hair through surfactant action (they also create the foam!). These surface-active agents (surf-act-ants) wrap themselves around dirt particles, helping to wash them away. Understanding the molecular structure of sulfates is a good place to start in understanding this property.

All sulfate surfactants work in essentially the same way: they are long molecular chains that don’t like water (hydrophobic), with a charged ‘sulfate’ end that loves water (hydrophilic). The long chains wrap around dirt, meaning that the water-loving sulfate end faces outwards. This makes the dirt water-soluble, and so it washes away down your drain [1].

Are all sulfates the same?

There are a number of sulfate surfactants commonly used in shampoos, but four of the most popular are:

  • Sodium Lauryl Sulfate (SLS)
  • Sodium Laureth Sulfate (SLES)
  • Ammonium Lauryl Sulfate (ALS)
  • Ammonium Laureth Sulfate (ALES)

Each of these removes dirt through the process described above, but they have different relative strengths. One way to measure the strength of a surfactant is the ‘Zein Test’ [2]. It shows that SLS and ALS are stronger surfactants than SLES and ALES – but also more irritating to the skin. You’re more likely to suffer from contact dermatitis using SLS/ALS than SLES/ALES but your hair will not be as “clean”.[3].

What are the potential risks?

The potential risks of sulfates can be a controversial topic because, for the vast majority of people, they are effectively harmless. There is no evidence that the use of sulfates in shampoos causes any systemic adverse effects in the short term or through accumulation, such as cancer, poor ocular development, cataract, or hair loss [4]. There is published evidence that if you repeatedly expose lab animals to surfactants, without rinsing them away, that long term damage is possible – but these studies clearly aren’t consistent with how shampoos are used.

This isn’t to say sulfates are harmless. They are known to cause skin irritation by damaging membrane proteins, which can be particularly harmful to those with dermatological conditions, such as psoriasis, seb derm, eczema or a dry scalp [5, 6]. Individuals with sensitive skin may experience stinging, burning, or redness with sulfates, although several studies have shown that it’s difficult to predict who will be affected [7].

Regulatory bodies in the US and EU regard sulfates in shampoos as safe, because of their low concentration and short exposure time [8, 9]. One slight exception is the European Medicines Agency (EMA), which requires pharmaceutical companies to add a warning to any medical product containing SLS due to the potential for irritation [10].

Sulfate myths

1. Sulfate-free shampoos are better for your health

The issue isn’t necessarily with sulfates, it’s with surfactants. There are many non-sulfate surfactants, but they carry the same irritant warnings while being less effective and more expensive. If you have reacted poorly to sulfate surfactants in the past, then you could consider trying the milder SLES or ALES, or an alternative such as coco-glucoside or sodium cocoyl-glycinate.

2. Sulfates are safe because they are made from coconut oil

Sulfates can be made from coconut oil, but the process isn’t a natural one. The Ziegler Process converts fatty acids to alcohols, with a methyl aluminoxane catalyst. These are then further processed into SLS (…and then into SLES using sulfur trioxide and chlorosulfuric acid) [11]. Not quite the same as extra virgin coconut oil!

3.  ‘Natural’ shampoo is better for your hair

The term ‘natural’ isn’t regulated in the EU or the US, and so your shampoo could still contain synthetic surfactants. If you want to ensure that what you’re using is the most appropriate for your hair, then you’ll need to become familiar with reading the label or reviews.

Should I use sulfate free shampoos?

Sulfates surfactants used in shampoos help to remove dirt and sebum, in order to clean your hair – the primary purpose of a shampoo. There is no evidence that they cause any systemic harm, but can be an irritant to those with sensitive skin or dermatological conditions. If you’ve reacted poorly to shampoo in the past, then it’s possible that a sulfate surfactant such as SLS was to blame.

It’s widely accepted that SLES and ALES are milder alternatives to SLS and ALS, and non-sulfate surfactants like sodium cocoyl glycinate exist (although they can still cause irritation). These milder alternatives can be found in mainstream products, but unfortunately, they aren’t yet separated neatly on shopping shelves. So you’ll need to check the ingredients – or let us do it for you!

How often should I wash using a sulfate free dandruff shampoo?

With any shampoo, you should always follow the guidance provided on the label.

But this isn’t always possible, with some manufacturers omitting key information.

To get some clarity on this, we asked Dr. Ben Barankin, a Toronto based board-certified dermatologist at the Toronto Dermatology Centre, for his advice, and he told us, “For mild-moderate dandruff, I recommend daily shampooing, and ideally alternating 3 shampoos, each with active anti-dandruff ingredients.”

Regular washing is important, as Board certified dermatologist Brent Thomas Goedjen M.D., founder of Live Oak Dermatology in Roswell, GA explains further, “A common misconception is that the skin flaking of seborrheic dermatitis is a result of dryness rather than a result of inflammation.  This leads patients to sometimes compensate by reducing the frequency of hair washing and attempting to rub off the scale. Unfortunately, this has the opposite of the intended effect by allowing conditions for yeast to flourish and therefore promoting the inflammation.  Rubbing the inflamed skin also contributes to perpetuating the problem.”

Dr. Matthew Zirwas, board-certified dermatologist and founder of Bexley Dermatology in Bexley, Ohio, recommended trying a shampoo for, “at least a month because if your old shampoo had ingredients that were causing a dandruff-like rash of their own, it will take 4-8 weeks for that ingredient to work its way out of your body after you start the new stuff.”

And if it doesn’t work, board-certified dermatologist Adam J. Friedman, MD, FAAD, assistant professor of dermatology and director of dermatologic research, Albert Einstein College of Medicine explains via the AAD, “For most people, dandruff does not require medical attention. However, sometimes the flaking and itching that appears like dandruff is actually a medical condition, such as seborrheic dermatitis, psoriasis, fungal infections of the scalp, or eczema. If you continue to have symptoms after using a dandruff shampoo, consult a board-certified dermatologist.”

By visiting a board-certified dermatologist, you can be properly diagnosed and be prescribed stronger medication than you can pick up at the pharmacy. As Dr. Ben Barankin says, “for moderate to severe cases of dandruff, a steroid shampoo or leave-in lotion can be prescribed. A prescription ciclopirox olamine lotion is often a nice option.”


[1] Trüeb, R. M. (2007). Shampoos: ingredients, efficacy and adverse effects. JDDG, 5(5), 356-365.

[2] Götte, E. (1964). Skin compatibility of tensides measured by their capacity for dissolving zein protein. pp. 83-90.

[3] Broze, G. (Ed.). (1999). Handbook of Detergents: Properties. CRC Press.

[4] Bondi, C. A., Marks, J. L., Wroblewski, L. B., Raatikainen, H. S., Lenox, S. R., & Gebhardt, K. E. (2015). Human and Environmental Toxicity of Sodium Lauryl Sulfate (SLS): Evidence for Safe Use in Household Cleaning Products. EHI, 9, 27.

[5] Törmä, H., Lindberg, M., & Berne, B. (2008). Skin barrier disruption by sodium lauryl sulfate-exposure alters the expressions of involucrin, transglutaminase 1, profilaggrin, and kallikreins during the repair phase in human skin in vivo. JID, 128(5), 1212-1219.

[6] MHRA. (2013). Aqueous cream: contains sodium lauryl sulfate which may cause skin reactions, particularly in children with eczema.

[7] Farage, M. A., Katsarou, A., & Maibach, H. I. (2006). Sensory, clinical and physiological factors in sensitive skin: a review. CD, 55(1), 1-14.

[8] FDA. (2015). CFR – Code of Federal Regulations Title 21. 21CFR172.822.

[9] European Union Council. (2009). Regulation (EC) No 1223/2009. Official Journal of the European Union, L 342/59.

[10] EMA. (2015). Background review for sodium lauryl sulfate used as an excipient. 351898/2014.

[11] Klahr, E., Trieselt, W., Trapp, H., & Widder, R. (1982). U.S. Patent No. 4,349,669. Washington, DC: U.S. Patent and Trademark Office.

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Master of Pharmacy

Ethan graduated a number of years ago after studying pharmacy in the UK, and is now a practicing pharmacist by day.

By night he writes the most stunning articles on a whole range of pharmaceutical subjects both here, and on our sister site at

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The site owner. I founded, and have ran this site for too many years now.
I have extremely sensitive skin, have suffered from seb derm for all my adult life and this site is my way of doing something about it.

Check out my sister site at

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